Recalling the Biological Significance of Immune Checkpoints on NK Cells: A Chance to Overcome LAG3, PD1, and CTLA4 Inhibitory Pathways by Adoptive NK Cell Transfer?

Immune checkpoint receptors (IC) positively or negatively regulate the activation of the host immune response, preventing unwanted reactions against self-healthy tissues. In recent years the term IC has been mainly used for the inhibitory ICs, which are critical to control Natural Killer (NK) and Cy...

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Bibliografiske detaljer
Udgivet i:Front Immunol
Main Authors: Lanuza, Pilar M., Pesini, Cecilia, Arias, Maykel A., Calvo, Carlota, Ramirez-Labrada, Ariel, Pardo, Julian
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6962251/
https://ncbi.nlm.nih.gov/pubmed/31998304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.03010
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