Recalling the Biological Significance of Immune Checkpoints on NK Cells: A Chance to Overcome LAG3, PD1, and CTLA4 Inhibitory Pathways by Adoptive NK Cell Transfer?

Immune checkpoint receptors (IC) positively or negatively regulate the activation of the host immune response, preventing unwanted reactions against self-healthy tissues. In recent years the term IC has been mainly used for the inhibitory ICs, which are critical to control Natural Killer (NK) and Cy...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Lanuza, Pilar M., Pesini, Cecilia, Arias, Maykel A., Calvo, Carlota, Ramirez-Labrada, Ariel, Pardo, Julian
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6962251/
https://ncbi.nlm.nih.gov/pubmed/31998304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.03010
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