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Multivalent Interactions with gp120 Are Required for the Anti-HIV Activity of Cyanovirin
Cyanovirin-N (CV-N) is a cyanobacterial lectin that binds to specific oligomannoses on the surface ofgp120, resulting in nanomolar antiviral activity against HIV. In its monomeric form, CV-N contains two functional carbohydrate-binding domains, A and B. When refolded at high concentration, the prote...
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| Publicado no: | Biopolymers |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6961781/ https://ncbi.nlm.nih.gov/pubmed/19235857 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bip.21173 |
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