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Interaction between somatic mutations and germline variants contributes to clinical heterogeneity in cancer

Deciphering principles of inter-tumoral heterogeneity is crucial for refinement of precision oncology. We have recently demonstrated that ‘oncogenic cooperation‘ between somatic mutations and regulatory germline variants can serve as a major cause for inter-tumoral heterogeneity, suggesting the requ...

詳細記述

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書誌詳細
出版年:Mol Cell Oncol
主要な著者: Musa, Julian, Grünewald, Thomas G. P.
フォーマット: Artigo
言語:Inglês
出版事項: Taylor & Francis 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6961672/
https://ncbi.nlm.nih.gov/pubmed/31993496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2019.1682924
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