A genome-wide long noncoding RNA CRISPRi screen identifies PRANCR as a novel regulator of epidermal homeostasis

Genome-wide association studies indicate that many disease susceptibility regions reside in non-protein-coding regions of the genome. Long noncoding RNAs (lncRNAs) are a major component of the noncoding genome, but their biological impacts are not fully understood. Here, we performed a CRISPR interf...

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Detalhes bibliográficos
Publicado no:Genome Res
Main Authors: Cai, Pengfei, Otten, Auke B.C., Cheng, Binbin, Ishii, Mitsuhiro A., Zhang, Wen, Huang, Beibei, Qu, Kun, Sun, Bryan K.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6961571/
https://ncbi.nlm.nih.gov/pubmed/31804951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.251561.119
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