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Robust differential microRNA targeting driven by supplementary interactions in vitro
Complementarity to the microRNA (miRNA) seed region has long been recognized as the primary determinant in target recognition by the Argonaute-miRNA complex. Recently, we reported that pairing to miRNA 3′-supplementary region (nucleotides 13–16) can increase target affinity by more than an order of...
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| Yayımlandı: | RNA |
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| Asıl Yazarlar: | , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Cold Spring Harbor Laboratory Press
2020
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6961540/ https://ncbi.nlm.nih.gov/pubmed/31732536 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.072264.119 |
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