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The L-platform/L-scaffold framework: a blueprint for RNA-cleaving nucleic acid enzyme design
We develop an L-platform/L-scaffold framework we hypothesize may serve as a blueprint to facilitate site-specific RNA-cleaving nucleic acid enzyme design. Building on the L-platform motif originally described by Suslov and coworkers, we identify new critical scaffolding elements required to anchor a...
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| Publicado no: | RNA |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6961537/ https://ncbi.nlm.nih.gov/pubmed/31776179 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.071894.119 |
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