Endothelial-specific deficiency of megalin in the brain protects mice against high-fat diet challenge

BACKGROUND: The increasing risk of obesity and diabetes among other metabolic disorders are the consequence of shifts in dietary patterns with high caloric-content food intake. We previously reported that megalin regulates energy homeostasis using blood-brain barrier (BBB) endothelial megalin-defici...

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Dades bibliogràfiques
Publicat a:J Neuroinflammation
Autors principals: Bartolome, Fernando, Antequera, Desiree, de la Cueva, Macarena, Rubio-Fernandez, Marcos, Castro, Nerea, Pascual, Consuelo, Camins, Antoni, Carro, Eva
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6961312/
https://ncbi.nlm.nih.gov/pubmed/31937343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-020-1702-2
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