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Molecular dynamics simulations on RORγt: insights into its functional agonism and inverse agonism
The retinoic acid receptor-related orphan receptor (ROR) γt receptor is a member of nuclear receptors, which is indispensable for the expression of pro-inflammatory cytokine IL-17. RORγt has been established as a drug target to design and discover novel treatments for multiple inflammatory and immun...
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| Publicat a: | Acta Pharmacol Sin |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Springer Singapore
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6961238/ https://ncbi.nlm.nih.gov/pubmed/31316175 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41401-019-0259-z |
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