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High content phenotypic screening identifies serotonin receptor modulators with selective activity upon breast cancer cell cycle and cytokine signaling pathways

Heterogeneity in disease mechanisms between genetically distinct patients contributes to high attrition rates in late stage clinical drug development. New personalized medicine strategies aim to identify predictive biomarkers which stratify patients most likely to respond to a particular therapy. Ho...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Bioorg Med Chem
मुख्य लेखकों: Warchal, Scott J., Dawson, John C., Shepherd, Emelie, Munro, Alison F., Hughes, Rebecca E., Makda, Ashraff, Carragher, Neil O.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Elsevier Science 2020
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6961118/
https://ncbi.nlm.nih.gov/pubmed/31757681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2019.115209
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