Differential roles of factors IX and XI in murine placenta and hemostasis under conditions of low tissue factor

The intrinsic tenase complex (FIXa-FVIIIa) of the intrinsic coagulation pathway and, to a lesser extent, thrombin-mediated activation of FXI, are necessary to amplify tissue factor (TF)-FVIIa–initiated thrombin generation. In this study, we determined the contribution of murine FIX and FXI to TF-dep...

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Bibliografske podrobnosti
izdano v:Blood Adv
Main Authors: Grover, Steven P., Schmedes, Clare M., Auriemma, Alyson C., Butler, Emily, Parrish, Molly L., Miszta, Adam, Cleuren, Audrey C., Visser, Mayken, Heitmeier, Stefan, Posma, Jens J., Spronk, Henri M., Antoniak, Silvio, Wolberg, Alisa S., Pawlinski, Rafal, Gailani, David, Mackman, Nigel
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2020
Teme:
Thrombosis and Hemostasis
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6960463/
https://ncbi.nlm.nih.gov/pubmed/31935292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2019000921
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