von Willebrand factor binding to myosin assists in coagulation

von Willebrand factor (VWF) binds to platelets and collagen as a means of facilitating coagulation at sites of injury. Recent evidence has shown that myosin can serve as a surface for thrombin generation and binds to activated factor V and factor X. We studied whether VWF can also bind myosin as a m...

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Bibliografiske detaljer
Udgivet i:Blood Adv
Main Authors: Flood, Veronica H., Slobodianuk, Tricia L., Keesler, Daniel, Lohmeier, Hannah K., Fahs, Scot, Zhang, Liyun, Simpson, Pippa, Montgomery, Robert R.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2020
Fag:
Thrombosis and Hemostasis
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6960459/
https://ncbi.nlm.nih.gov/pubmed/31935285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2019000533
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