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Human chromosome‐specific aneuploidy is influenced by DNA‐dependent centromeric features

Intrinsic genomic features of individual chromosomes can contribute to chromosome‐specific aneuploidy. Centromeres are key elements for the maintenance of chromosome segregation fidelity via a specialized chromatin marked by CENP‐A wrapped by repetitive DNA. These long stretches of repetitive DNA va...

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Bibliografische gegevens
Gepubliceerd in:EMBO J
Hoofdauteurs: Dumont, Marie, Gamba, Riccardo, Gestraud, Pierre, Klaasen, Sjoerd, Worrall, Joseph T, De Vries, Sippe G, Boudreau, Vincent, Salinas‐Luypaert, Catalina, Maddox, Paul S, Lens, Susanne MA, Kops, Geert JPL, McClelland, Sarah E, Miga, Karen H, Fachinetti, Daniele
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2019
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6960447/
https://ncbi.nlm.nih.gov/pubmed/31750958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2019102924
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