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Centromeric SMC1 promotes centromere clustering and stabilizes meiotic homolog pairing

During meiosis, each chromosome must selectively pair and synapse with its own unique homolog to enable crossover formation and subsequent segregation. How homolog pairing is maintained in early meiosis to ensure synapsis occurs exclusively between homologs is unknown. We aimed to further understand...

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Détails bibliographiques
Publié dans:PLoS Genet
Auteurs principaux: Hatkevich, Talia, Boudreau, Vincent, Rubin, Thomas, Maddox, Paul S., Huynh, Jean-René, Sekelsky, Jeff
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6812850/
https://ncbi.nlm.nih.gov/pubmed/31609962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008412
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