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Insulin suppresses transcriptional activity of yes-associated protein in insulin target cells

Yes-associated protein (YAP), the main transcriptional coactivator of the Hippo pathway, integrates multiple inputs from different signaling cascades. Evidence implicates YAP in the control of cellular nutrient and energy status, but the underlying mechanisms are not fully elucidated. Here we show t...

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Pubblicato in:Mol Biol Cell
Autori principali: Sayedyahossein, Samar, Hedman, Andrew C., Sacks, David B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6960410/
https://ncbi.nlm.nih.gov/pubmed/31693448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E19-04-0205
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