Neuronal nitric oxide synthase regulation of calcium cycling in ventricular cardiomyocytes is independent of Ca(v)1.2 channel modulation under basal conditions

Neuronal nitric oxide synthase (nNOS) is considered a regulator of Ca(v)1.2 L-type Ca(2+) channels and downstream Ca(2+) cycling in the heart. The commonest view is that nitric oxide (NO), generated by nNOS activity in cardiomyocytes, reduces the currents through Ca(v)1.2 channels. This gives rise t...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Pflugers Arch
Prif Awduron: Ebner, Janine, Cagalinec, Michal, Kubista, Helmut, Todt, Hannes, Szabo, Petra L., Kiss, Attila, Podesser, Bruno K., Cserne Szappanos, Henrietta, Hool, Livia C., Hilber, Karlheinz, Koenig, Xaver
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Springer Berlin Heidelberg 2019
Pynciau:
Ion Channels, Receptors and Transporters
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6960210/
https://ncbi.nlm.nih.gov/pubmed/31822999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-019-02335-7
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