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L-type Ca(2+) channel-mediated Ca(2+)-influx adjusts neuronal mitochondrial function to physiological and pathophysiological conditions

L-type voltage-gated Ca(2+) channels (LTCCs) are implicated in neurodegenerative processes and cell death. Accordingly, LTCC antagonists have been proposed to be neuroprotective although this view is disputed, because intentional LTCC activation can also have beneficial effects. LTCC-mediated Ca(2+)...

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Bibliografische gegevens
Gepubliceerd in:Sci Signal
Hoofdauteurs: Hotka, Matej, Cagalinec, Michal, Hilber, Karlheinz, Hool, Livia, Boehm, Stefan, Kubista, Helmut
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7116774/
https://ncbi.nlm.nih.gov/pubmed/32047116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aaw6923
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