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Nanopore direct RNA sequencing maps the complexity of Arabidopsis mRNA processing and m(6)A modification

Understanding genome organization and gene regulation requires insight into RNA transcription, processing and modification. We adapted nanopore direct RNA sequencing to examine RNA from a wild-type accession of the model plant Arabidopsis thaliana and a mutant defective in mRNA methylation (m(6)A)....

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Pubblicato in:eLife
Autori principali: Parker, Matthew T, Knop, Katarzyna, Sherwood, Anna V, Schurch, Nicholas J, Mackinnon, Katarzyna, Gould, Peter D, Hall, Anthony JW, Barton, Geoffrey J, Simpson, Gordon G
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6959997/
https://ncbi.nlm.nih.gov/pubmed/31931956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.49658
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