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How well do RNA-Seq differential gene expression tools perform in a complex eukaryote? A case study in Arabidopsis thaliana

MOTIVATION: RNA-seq experiments are usually carried out in three or fewer replicates. In order to work well with so few samples, differential gene expression (DGE) tools typically assume the form of the underlying gene expression distribution. In this paper, the statistical properties of gene expres...

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Detalhes bibliográficos
Publicado no:Bioinformatics
Main Authors: Froussios, Kimon, Schurch, Nick J, Mackinnon, Katarzyna, Gierliński, Marek, Duc, Céline, Simpson, Gordon G, Barton, Geoffrey J
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6748783/
https://ncbi.nlm.nih.gov/pubmed/30726870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btz089
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