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Structural basis of substrate recognition by a polypeptide processing and secretion transporter

The peptidase-containing ATP-binding cassette transporters (PCATs) are unique members of the ABC transporter family that proteolytically process and export peptides and proteins. Each PCAT contains two peptidase domains that cleave off the secretion signal, two transmembrane domains forming a transl...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Kieuvongngam, Virapat, Olinares, Paul Dominic B, Palillo, Anthony, Oldham, Michael L, Chait, Brian T, Chen, Jue
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6959990/
https://ncbi.nlm.nih.gov/pubmed/31934861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.51492
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