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Novel protection–deprotection strategies in diazeniumdiolate chemistry: synthesis of V-IPA/NO
Synthesis of previously inaccessible, potentially liver selective HNO donor V-IPA/NO ([iPrHN(3)–N(1)(O(1))=N(2)–O(2)–R], where R = vinyl) is reported here. A novel fluoride-labile TOM group at O-2 in conjunction with MOM protection at N-3 in IPA/NO is employed. The strategy developed is also extende...
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| Publicado no: | Chem Commun (Camb) |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6959522/ https://ncbi.nlm.nih.gov/pubmed/21556407 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c1cc12130h |
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