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A general approach to detect gene (G)-environment (E) additive interaction leveraging G-E independence in case-control studies

It is increasingly of interest in statistical genetics to test for the presence of an additive interaction between genetic (G) and environmental (E) risk factors. In case-control studies involving a rare disease, a statistical test of no additive G × E interaction typically entails a test of no rela...

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Détails bibliographiques
Publié dans:Stat Med
Auteurs principaux: Tchetgen Tchetgen, Eric J., Shi, Xu, Wong, Benedict H.W., Sofer, Tamar
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6959489/
https://ncbi.nlm.nih.gov/pubmed/31441522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.8337
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