Likelihood Ratio Test for Detecting Gene (G)-Environment (E) Interactions Under an Additive Risk Model Exploiting G-E Independence for Case-Control Data

There has been a long-standing controversy in epidemiology with regard to an appropriate risk scale for testing interactions between genes (G) and environmental exposure (E ). Although interaction tests based on the logistic model—which approximates the multiplicative risk for rare diseases—have bee...

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Detalhes bibliográficos
Main Authors: Han, Summer S., Rosenberg, Philip S., Garcia-Closas, Montse, Figueroa, Jonine D., Silverman, Debra, Chanock, Stephen J., Rothman, Nathaniel, Chatterjee, Nilanjan
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Practice of Epidemiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3571244/
https://ncbi.nlm.nih.gov/pubmed/23118105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/aje/kws166
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