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Leveraging Methylome-Environment Interaction to Detect Genetic Determinants of Disease

OBJECTIVE: The association between DNA methylation and a trait of interest may depend on an environmental exposure, and incorrectly accounting for this dependence can lead to a reduction in power of the standard tests used in epigenome-wide association studies. We present the M-ME test to jointly te...

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Detalhes bibliográficos
Publicado no:Hum Hered
Main Authors: Slade, Emily, Kraft, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5621601/
https://ncbi.nlm.nih.gov/pubmed/27490128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000447357
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