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Leveraging Methylome-Environment Interaction to Detect Genetic Determinants of Disease
OBJECTIVE: The association between DNA methylation and a trait of interest may depend on an environmental exposure, and incorrectly accounting for this dependence can lead to a reduction in power of the standard tests used in epigenome-wide association studies. We present the M-ME test to jointly te...
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| Published in: | Hum Hered |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5621601/ https://ncbi.nlm.nih.gov/pubmed/27490128 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000447357 |
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