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Leveraging phenotypic variability to identify genetic interactions in human phenotypes

Although thousands of loci have been associated with human phenotypes, the role of gene-environment (GxE) interactions in determining individual risk of human diseases remains unclear. This is partly because of the severe erosion of statistical power resulting from the massive number of statistical...

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Bibliografiske detaljer
Udgivet i:Am J Hum Genet
Main Authors: Marderstein, Andrew R., Davenport, Emily R., Kulm, Scott, Van Hout, Cristopher V., Elemento, Olivier, Clark, Andrew G.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7820920/
https://ncbi.nlm.nih.gov/pubmed/33326753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2020.11.016
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