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Multifaceted role of SMCR8 as autophagy regulator

Through autophagy intracellular material is engulfed by double membrane vesicles and delivered to lysosomes for degradation. This process requires Rab GTPases, Rab GAPs and Rab GEFs for proper membrane trafficking, since they control vesicle budding, targeting and fusion. Deregulation of autophagy c...

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Bibliografiske detaljer
Udgivet i:Small GTPases
Main Authors: Jung, Jennifer, Behrends, Christian
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6959302/
https://ncbi.nlm.nih.gov/pubmed/28696821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541248.2017.1346553
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