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Opposite functions of STAT3 and Smad3 in regulating Tiam1 expression in Th17 cells
We recently showed that Tiam1 expression is induced in pro-inflammatory T helper 17 (Th17) cells differentiated with interleukin (IL)-6 and TGF-β1, and together with Rac1 promote Th17 cell development and autoimmunity in a mouse model of multiple sclerosis. Here we found that STAT3 and Smad3, downst...
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| Publicado no: | Small GTPases |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6959293/ https://ncbi.nlm.nih.gov/pubmed/28609201 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541248.2017.1341365 |
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