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Targeting Ras signaling in AML: RALB is a small GTPase with big potential

Acute myeloid leukemia (AML) is a devastating malignancy for which novel treatment approaches are desperately needed. Ras signaling is an attractive therapeutic target for AML because a large proportion of AMLs have mutations in NRAS, KRAS, or genes that activate Ras signaling, and key Ras effectors...

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Dades bibliogràfiques
Publicat a:Small GTPases
Autors principals: Pomeroy, Emily J., Eckfeldt, Craig E.
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6959283/
https://ncbi.nlm.nih.gov/pubmed/28682649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541248.2017.1339765
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