RALB provides critical survival signals downstream of Ras in acute myeloid leukemia

Mutations that activate RAS proto-oncogenes and their effectors are common in acute myeloid leukemia (AML); however, efforts to therapeutically target Ras or its effectors have been unsuccessful, and have been hampered by an incomplete understanding of which effectors are required for AML proliferat...

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Detaylı Bibliyografya
Yayımlandı:Oncotarget
Asıl Yazarlar: Eckfeldt, Craig E., Pomeroy, Emily J., Lee, Robin D.W., Hazen, Katherine S., Lee, Lindsey A., Moriarity, Branden S., Largaespada, David A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Impact Journals LLC 2016
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5323144/
https://ncbi.nlm.nih.gov/pubmed/27556501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11431
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