The ETS transcription factor ETV5 is a target of activated ALK in neuroblastoma contributing to increased tumour aggressiveness

Neuroblastoma is an aggressive childhood cancer arising from sympatho-adrenergic neuronal progenitors. The low survival rates for high-risk disease point to an urgent need for novel targeted therapeutic approaches. Detailed molecular characterization of the neuroblastoma genomic landscape indicates...

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Udgivet i:Sci Rep
Main Authors: Mus, Liselot M., Lambertz, Irina, Claeys, Shana, Kumps, Candy, Van Loocke, Wouter, Van Neste, Christophe, Umapathy, Ganesh, Vaapil, Marica, Bartenhagen, Christoph, Laureys, Genevieve, De Wever, Olivier, Bexell, Daniel, Fischer, Matthias, Hallberg, Bengt, Schulte, Johannes, De Wilde, Bram, Durinck, Kaat, Denecker, Geertrui, De Preter, Katleen, Speleman, Frank
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6959226/
https://ncbi.nlm.nih.gov/pubmed/31937834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-57076-5
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