Sesamin, a Naturally Occurring Lignan, Inhibits Ligand-Induced Lipogenesis through Interaction with Liver X Receptor Alpha (LXRα) and Pregnane X Receptor (PXR)

Liver X receptor (LXR) is a nuclear receptor that regulates various biological processes, including de novo lipogenesis, cholesterol metabolism, and inflammation. Selective inhibition of LXR may aid the treatment of nonalcoholic fatty liver disease (NAFLD). Sesamin is a naturally occurring lignan in...

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Detalhes bibliográficos
Publicado no:Evid Based Complement Alternat Med
Main Authors: Tai, Tsai-Sung, Tien, Ni, Shen, Hsin-Yi, Chu, Fang-Yi, Wang, Charles C. N., Lu, Chieh-Hsiang, Yu, Hui-I, Kung, Fang-Ping, Chuang, Hsiang-Hsun, Lee, Ying-Ray, Chang, Hsiao-Yun, Lim, Yun-Ping
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6959160/
https://ncbi.nlm.nih.gov/pubmed/31976003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/9401648
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