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Unbiased Thiol-Labeling and Top-Down Proteomic Analyses Implicate Multiple Proteins in the Late Steps of Regulated Secretion

Regulated exocytosis enables temporal and spatial control over the secretion of biologically active compounds; however, the mechanism by which Ca(2+) modulates different stages of exocytosis is still poorly understood. For an unbiased, top-down proteomic approach, select thiol- reactive reagents wer...

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Detalhes bibliográficos
Publicado no:Proteomes
Main Authors: Furber, Kendra L., Backlund, Peter S., Yergey, Alfred L., Coorssen, Jens R.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6958363/
https://ncbi.nlm.nih.gov/pubmed/31569819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/proteomes7040034
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