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Proteomics Is Analytical Chemistry: Fitness-for-Purpose in the Application of Top-Down and Bottom-Up Analyses

Molecular mechanisms underlying health and disease function at least in part based on the flexibility and fine-tuning afforded by protein isoforms and post-translational modifications. The ability to effectively and consistently resolve these protein species or proteoforms, as well as assess quantit...

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Pubblicato in:Proteomes
Autori principali: Coorssen, Jens R., Yergey, Alfred L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5217385/
https://ncbi.nlm.nih.gov/pubmed/28248279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/proteomes3040440
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