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Knockdown of SALL4 overcomes cisplatin-resistance through AKT/mTOR signaling in lung cancer cells

Drug resistance is an important factor for the poor prognosis of non-small cell lung cancer (NSCLC). Sal-like protein 4 (Sall4) is a stem cell marker, and plays a role in maintaining self-renewal. Previous studies have demonstrated that Sall4 may be a candidate for use as support in the diagnosis of...

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Bibliografske podrobnosti
izdano v:Int J Clin Exp Pathol
Main Authors: Jiang, Gang, Liu, Chen-Tao
Format: Artigo
Jezik:Inglês
Izdano: e-Century Publishing Corporation 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6958024/
https://ncbi.nlm.nih.gov/pubmed/31938149
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