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HtrA1 up-regulates expression of MMPs via Erk1/2/Rock-dependent pathways

Background: There are few studies that have identified the potential role of a high temperature requirement A1 (HtrA1) in intervertebral disc degeneration (IDD). This study was undertaken to investigate the regulatory role of HtrA1 in the pathogenesis of IDD. Material and Methods: The mRNA levels of...

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Publicat a:Int J Clin Exp Pathol
Autors principals: Li, Dapeng, Yue, Jiawei, Wu, Yan, Barnie, Prince Amoah, Wu, Yumin
Format: Artigo
Idioma:Inglês
Publicat: e-Century Publishing Corporation 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6958014/
https://ncbi.nlm.nih.gov/pubmed/31938194
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