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HtrA4 is up-regulated during trophoblast syncytialization and BeWo cells fail to syncytialize without HtrA4

The outer layer of the human placenta comprises syncytiotrophoblast, which forms through fusion of cytotrophoblasts (syncytialization), and plays a critical role in maternal–fetal communication including nutrient/oxygen transportation and hormone secretion. Impairment in syncytialization inevitably...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Mansilla, Mary, Wang, Yao, Lim, Rebecca, Palmer, Kirsten, Nie, Guiying
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8277827/
https://ncbi.nlm.nih.gov/pubmed/34257367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-93520-1
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