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Proliferative Signaling by ERBB proteins and RAF/MEK/ERK effectors in Polycystic Kidney Disease

A primary pathological feature of polycystic kidney disease (PKD) is the hyperproliferation of epithelial cells in renal tubules, resulting in formation of fluid-filled cysts. The proliferative aspects of the two major forms of PKD—autosomal dominant PKD (ADPKD), which arises from mutations in the p...

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Vydáno v:Cell Signal
Hlavní autoři: Parker, Mitchell I., Nikonova, Anna S., Sun, Danlin, Golemis, Erica A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6957738/
https://ncbi.nlm.nih.gov/pubmed/31830556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2019.109497
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