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Proliferative Signaling by ERBB proteins and RAF/MEK/ERK effectors in Polycystic Kidney Disease
A primary pathological feature of polycystic kidney disease (PKD) is the hyperproliferation of epithelial cells in renal tubules, resulting in formation of fluid-filled cysts. The proliferative aspects of the two major forms of PKD—autosomal dominant PKD (ADPKD), which arises from mutations in the p...
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| Publicado en: | Cell Signal |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6957738/ https://ncbi.nlm.nih.gov/pubmed/31830556 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2019.109497 |
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