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B cell ADAM17 Controls T cell Independent Humoral Immune Responses through Regulation of TACI and CD138

ADAM17 is known to contribute to the immune system through its shedding of tumor necrosis factor alpha (TNFα). However, the role of ADAM17 in B cell biology is not well characterized. To determine whether B cell ADAM17 contributes to T cell-independent humoral immune responses, we crossed CD19 Cre t...

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Publicat a:Biochem Biophys Res Commun
Autors principals: Lownik, Joseph C., Wimberly, Jessica, Takahashi-Ruiz, Leila, Martin, Rebecca K.
Format: Artigo
Idioma:Inglês
Publicat: 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6957701/
https://ncbi.nlm.nih.gov/pubmed/31771880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2019.11.124
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