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B cell ADAM10 controls murine lupus progression through regulation of the ICOS:ICOS-ligand axis.
The role of inducible costimulator (ICOS) and its ligand (ICOSL) have both been shown to be essential for proper humoral responses as well as autoimmune antibody development in mouse models of lupus. Here we report a specific role for the metalloprotease ADAM10 on B cells in regulating both ICOSL an...
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| Yayımlandı: | J Immunol |
|---|---|
| Asıl Yazarlar: | , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2019
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6344316/ https://ncbi.nlm.nih.gov/pubmed/30610163 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1801207 |
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