Noninvasive rapid detection of metabolic adaptation in activated human T lymphocytes by hyperpolarized (13)C magnetic resonance

The metabolic shift induced in human CD4(+) T lymphocytes by stimulation is characterized by an upregulation of glycolysis, leading to an augmentation in lactate production. This adaptation has already been highlighted with various techniques and reported in several previous studies. We herein propo...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Can, Emine, Mishkovsky, Mor, Yoshihara, Hikari A. I., Kunz, Nicolas, Couturier, Dominique-Laurent, Petrausch, Ulf, Doucey, Marie-Agnès, Comment, Arnaud
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6957688/
https://ncbi.nlm.nih.gov/pubmed/31932697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-57026-1
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