Impact of the Na(V)1.8 variant, A1073V, on post-sigmoidectomy pain and electrophysiological function in rat sympathetic neurons

Na(V)1.8 channels play a crucial role in regulating the action potential in nociceptive neurons. A single nucleotide polymorphism in the human Na(V)1.8 gene SCN10A, A1073V (rs6795970, G>A), has been linked to the diminution of mechanical pain sensation as well as cardiac conduction abnormalities....

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Detalhes bibliográficos
Publicado no:J Neurophysiol
Main Authors: Coates, Matthew D., Kim, Joyce S., Carkaci-Salli, Nurgul, Vrana, Kent E., Koltun, Walter A., Puhl, Henry L., Adhikary, Sanjib D., Janicki, Piotr K., Ruiz-Velasco, Victor
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6957366/
https://ncbi.nlm.nih.gov/pubmed/31642403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00542.2019
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