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Immunological characterization of HM5023507, an orally active PI3Kδ/γ inhibitor
Phosphoinositide 3‐kinases, delta (PI3Kδ) and gamma (PI3Kγ) are enriched in immune cells and regulate the development and function of innate and adaptive immunity. Dual PI3Kδγ inhibitors are considered high value targets for their potential to treat a variety of immune‐mediated diseases, but their d...
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| Опубликовано в: : | Pharmacol Res Perspect |
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| Главные авторы: | , , , , , , , , , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
John Wiley and Sons Inc.
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6957347/ https://ncbi.nlm.nih.gov/pubmed/31956418 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.559 |
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