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ROCK2 inhibition enhances the thermogenic program in white and brown fat tissue in mice

The RhoA/ROCK-mediated actin cytoskeleton dynamics have been implicated in adipogenesis. The two ROCK isoforms, ROCK1 and ROCK2, are highly homologous. The contribution of ROCK2 to adipogenesis in vivo has not been elucidated. The present study aimed at the in vivo and in vitro roles of ROCK2 in the...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Wei, Lei, Surma, Michelle, Yang, Yang, Tersey, Sarah, Shi, Jianjian
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6956740/
https://ncbi.nlm.nih.gov/pubmed/31914704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201901174RR
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