Stasimon Contributes to the Loss of Sensory Synapses and Motor Neuron Death in a Mouse Model of Spinal Muscular Atrophy

Reduced expression of the survival motor neuron (SMN) protein causes the neurodegenerative disease spinal muscular atrophy (SMA). Here, we show that adeno-associated virus serotype 9 (AAV9)-mediated delivery of Stasimon—a gene encoding an endoplasmic reticulum (ER)-resident transmembrane protein reg...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Rep
Egile Nagusiak: Simon, Christian M., Van Alstyne, Meaghan, Lotti, Francesco, Bianchetti, Elena, Tisdale, Sarah, Watterson, D. Martin, Mentis, George Z., Pellizzoni, Livio
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2019
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6956708/
https://ncbi.nlm.nih.gov/pubmed/31851921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.11.058
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