Clinical and Immunologic Biomarkers for Histologic Regression of High-Grade Cervical Dysplasia and Clearance of HPV16 and HPV18 after Immunotherapy

PURPOSE: As previously reported, treatment of high-grade cervical dysplasia with VGX-3100 resulted in complete histopatho-logic regression (CR) concomitant with elimination of HPV16/18 infection in 40.0% of VGX-3100–treated patients compared with only 14.3% in placebo recipients in a randomized phas...

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Vydáno v:Clin Cancer Res
Hlavní autoři: Morrow, Matthew P., Kraynyak, Kimberly A., Sylvester, Albert J., Dallas, Michael, Knoblock, Dawson, Boyer, Jean D., Yan, Jian, Vang, Russell, Khan, Amir S., Humeau, Laurent, Sardesai, Niranjan Y., Kim, J. Joseph, Plotkin, Stanley, Weiner, David B., Trimble, Cornelia L., Bagarazzi, Mark L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6956401/
https://ncbi.nlm.nih.gov/pubmed/29084917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-17-2335
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