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Sugar and Polymer Excipients Enhance Uptake and Splice-Switching Activity of Peptide-Dendrimer/Lipid/Oligonucleotide Formulations

Non-viral transfection vectors are commonly used for oligonucleotide (ON) delivery but face many challenges before reaching the desired compartments inside cells. With the support of additional compounds, it might be more feasible for a vector to endure the barriers and achieve efficient delivery. I...

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Vydáno v:Pharmaceutics
Hlavní autoři: Saher, Osama, Lehto, Taavi, Gissberg, Olof, Gupta, Dhanu, Gustafsson, Oskar, Andaloussi, Samir EL, Darbre, Tamis, Lundin, Karin E., Smith, C. I. Edvard, Zain, Rula
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6955847/
https://ncbi.nlm.nih.gov/pubmed/31835435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics11120666
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