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Sugar and Polymer Excipients Enhance Uptake and Splice-Switching Activity of Peptide-Dendrimer/Lipid/Oligonucleotide Formulations

Non-viral transfection vectors are commonly used for oligonucleotide (ON) delivery but face many challenges before reaching the desired compartments inside cells. With the support of additional compounds, it might be more feasible for a vector to endure the barriers and achieve efficient delivery. I...

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Bibliographische Detailangaben
Veröffentlicht in:Pharmaceutics
Hauptverfasser: Saher, Osama, Lehto, Taavi, Gissberg, Olof, Gupta, Dhanu, Gustafsson, Oskar, Andaloussi, Samir EL, Darbre, Tamis, Lundin, Karin E., Smith, C. I. Edvard, Zain, Rula
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6955847/
https://ncbi.nlm.nih.gov/pubmed/31835435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics11120666
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