Population pharmacokinetics of sildenafil in extremely premature infants

AIMS: To characterize the population pharmacokinetics (PK) of sildenafil and its active metabolite, N‐desmethyl sildenafil (DMS), in premature infants. METHODS: We performed a multicentre, open‐label trial to characterize the PK of sildenafil in infants ≤28 weeks gestation and < 365 postnatal day...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Br J Clin Pharmacol
Main Authors: Gonzalez, Daniel, Laughon, Matthew M., Smith, P. Brian, Ge, Shufan, Ambalavanan, Namasivayam, Atz, Andrew, Sokol, Gregory M., Hornik, Chi D., Stewart, Dan, Mundakel, Gratias, Poindexter, Brenda B., Gaedigk, Roger, Mills, Mary, Cohen‐Wolkowiez, Michael, Martz, Karen, Hornik, Christoph P.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2019
Teme:
Original Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6955411/
https://ncbi.nlm.nih.gov/pubmed/31475367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.14111
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki