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Mycobacterial HflX is a ribosome splitting factor that mediates antibiotic resistance

Antibiotic resistance in bacteria is typically conferred by proteins that function as efflux pumps or enzymes that modify either the drug or the antibiotic target. Here we report an unusual mechanism of resistance to macrolide-lincosamide antibiotics mediated by mycobacterial HflX, a conserved ribos...

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Rudra, Paulami, Hurst-Hess, Kelley R., Cotten, Katherine L., Partida-Miranda, Andrea, Ghosh, Pallavi
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6955381/
https://ncbi.nlm.nih.gov/pubmed/31871194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1906748117
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