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Mycobacterial HflX is a ribosome splitting factor that mediates antibiotic resistance
Antibiotic resistance in bacteria is typically conferred by proteins that function as efflux pumps or enzymes that modify either the drug or the antibiotic target. Here we report an unusual mechanism of resistance to macrolide-lincosamide antibiotics mediated by mycobacterial HflX, a conserved ribos...
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| 出版年: | Proc Natl Acad Sci U S A |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6955381/ https://ncbi.nlm.nih.gov/pubmed/31871194 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1906748117 |
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