The conserved GTPase HflX is a ribosome splitting factor that binds to the E-site of the bacterial ribosome

Using a combination of biochemical, structural probing and rapid kinetics techniques we reveal for the first time that the universally conserved translational GTPase (trGTPase) HflX binds to the E-site of the 70S ribosome and that its GTPase activity is modulated by peptidyl transferase centre (PTC)...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Autores principales: Coatham, Mackenzie L., Brandon, Harland E., Fischer, Jeffrey J., Schümmer, Tobias, Wieden, Hans-Joachim
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2016
Materias:
Structural Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4770234/
https://ncbi.nlm.nih.gov/pubmed/26733579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv1524
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